The Marçal Vilar Lab

Research in the marcalvilarlab focuses on understanding the mechanism of neurotrophin receptors activation and signaling and their role in neurodegeneration. We use different biochemical, biophysical, and molecular biology approaches to study fundamental processes like receptor oligomerization, protein-protein interactions, cell signaling, and neuronal cell death. The ultimate goal of our work is to understand how a neuron integrates all input signals that receive from the neurotrophins during normal development and how this process is compromised during degeneration diseases.